Design and Development of a Next-Generation Modelling and Simulation Platform for Cancer Systems Biology
|Status||On Going Project|
|Progress Report||View Progress Report|
The proposed project outlines the design and development of a next generation multiscale modelling platform for applications in cancer systems biology. This modelling platform envisages a seamless integration of next generation sequencing and quantitation data from the wet labs and its onward usage for investigating the roles of known oncological factors. A powerful HPC enabled simulation engine will be developed and coupled with an intuitive and customizable GUI. To facilitate in the modelling of complex oncological phenomenon, a programmable interface to the engine and GUI will also be developed. A thorough case study model will also be constructed and made publically available, for exemplifying the rich modelling features provided by the modelling platform. The resulting software and case study model will be made available to the laboratories, research centers, universities as well as the pharmaceutical companies which are aiming to develop or evaluate therapeutic targets as well as drugs for treatment of cancer patients. Upon deployment, the proposed modelling platform will not only assist in the modelling of next generation cancer systems biology data, but will also significantly enhance the throughput of the model building and simulation processes.